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Anti-IL5RAPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-IL5RA Polyclonal Antibody品牌：solarbio | 貨號：K005909P

英文名稱Anti-IL5RA Polyclonal Antibody
宿主Rabbit
別名CD125;CDw125;HSIL5R3;IL5R
應用WB
稀釋比例WB 1:500-2000.
交叉反應 Human Mouse Rat
蛋白分子量48kDa
Gene ID3568
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human IL5RA
性狀液體
Public Immunogen RangeRecombinant protein of human IL5RA
Subcellular LocationsMembrane Single-pass type I membrane protein
Swiss ProtQ01344
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

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