人妻一区二区中文字幕在线-大肉棒抽插小嫩穴视频免费-国产福利萌白酱视频资源福利-最新国产主播一区二区-伊人五月天婷婷成人-色av中文字幕在线-美女打开小穴让男生操的视频-国产又长又粗又长又爽毛片-人人妻人人澡人人爽欧美三区

CD80(B7-1,BB1)和CD86(B7-2,B70)是B7細(xì)胞表面配體家族的成員，可調(diào)節(jié)T細(xì)胞激活和免疫應(yīng)答。CD80在激活的抗原呈遞細(xì)胞中表達(dá)，包括樹(shù)突細(xì)胞、B細(xì)胞、單核細(xì)胞和巨噬細(xì)胞。CD86在休眠單核細(xì)胞、樹(shù)突細(xì)胞、激活的B淋巴細(xì)胞中表達(dá)，在有炎癥的情況下進(jìn)一步上調(diào)。CD80和CD86均為CD28的配體，CD28是一種T細(xì)胞共刺激受體。CD28與CD80或CD86的相互作用提供初始T細(xì)胞激活、T細(xì)胞增殖以及獲得效應(yīng)子功能所需的第二信號(hào)。或者，CD80和CD86還是CTLA-4的配體，這會(huì)導(dǎo)致T細(xì)胞活性下調(diào)。

產(chǎn)品名稱(chēng)

Anti-CD86 Antibody (FITC), Mouse Monoclonal

經(jīng)驗(yàn)證的應(yīng)用

FCM

交叉反應(yīng)

Reacts with: Rat

特異性

Rat CD86

免疫原

Recombinant Rat CD86 Protein (Catalog#80025-R08H)

制備方法

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD86 (rR CD86; Catalog#80025-R08H; NP_064466.1; Met1-Ile250) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

來(lái)源

Monoclonal Mouse IgG2b Clone #10

純化

Protein A

緩沖液

Aqueous solution containing 0.5% BSA and 0.09% sodium azide